Dr. Arif Engin Çetin and his collaborators developed a plasmonic platform that can precisely measure cell growth, and published their study in the prestigious journal ACS Nano.
Accessing cell growth is critical for identifying the biophysical properties of cells and their therapeutic response to drug therapies. Common techniques used to detect the biophysical properties of cells may have some drawbacks, for example in sensitivity and reliability.
In their latest study published in one of the most important journals in the field; Dr. Çetin, group leader of the Nanophotonics and Biodetection Systems Lab at IBG, and his collaborators Dr. Ali Khademhosseini from Terasaki Institute for Biomedical Innovation, Assoc. Prof. Seda Nur Topkaya from Izmir Katip Çelebi University, Assoc. Prof. Özden Yalçın Özuysal from Izmir Institute of Technology introduced a plasmonic platform that can precisely measure cell weight and the dynamic change in real-time. The system can determine growth rates of individual cells within only 10 minutes to map the growth profile of populations.
Moreover, the platform could successfully determine heterogeneity within the growth profile of populations and assess subpopulations exhibiting distinct growth profiles.
By rapidly determining cell growth kinetics in small samples, this growth-profiling platform could be of broad use to basic research and clinical applications.