IBG-PHARMA Platform
You can contact us directly for the services you request from IBG-Pharma.
Personnel
IBG-PHARMA Platform
Platform Director
Mehmet İNAN
mehmet.inan@ibg.edu.tr
+90 232 299 41 00
(1004 - 5271)
+9
02322994114
Sibel KALYONCU
Analytical Development and Characterization Manager
sibel.kalyoncu@ibg.edu.tr
+90 232 299 41
00
(5181)
0 (232) 299 41 68
Hüseyin AKINTÜRK
Research Technician
huseyin.akinturk@ibg.edu.tr
Rıdvan ÖRKÜT
R&D Personnel
ridvan.orkut@ibg.edu.tr
+90 232 299 41
00
(4001)
Olcay MERT
R&D Personnel
olcay.mert@ibg.edu.tr
Doğu SAYILI
Molecular Cell Biologist
dogu.sayili@ibg.edu.tr
0 (232) 299 _ _
Ayça ZEYBEK KUYUCU
Researcher
ayca.zeybekkuyucu@ibg.edu.tr
Şeyda GÜLLÜ
Researcher
seyda.gullu@ibg.edu.tr
Ender AVCI
Researcher
ender.avci@ibg.edu.tr
+90 232 299 41
00
(2501)
0 (232) 299 4191
İbrahim Oğuzhan TARMAN
Researcher
oguzhan.tarman@ibg.edu.tr
Ali Mert SENCER
PhD Student
mert.sencer@ibg.edu.tr
Umut HASKÖK
MSc Student
umut.haskok@ibg.edu.tr
Ege TEKİN
MSc Student
ege.tekin@ibg.edu.tr
Buse BAYSEÇKİN
MSc Student
buse.bayseckin@std.ibg.edu.tr
Ayşe GÜNBAŞ
Visiting Researcher
None
Latife Merve OKTAY ÇELEBİ
Visiting Researcher
latife.oktaycelebi@ibg.edu.tr
Ceren ÖZER ÇOKGEZME
Researcher
ceren.ozer@ibg.edu.tr
Noorhamizah SUHAIMI
Researcher
noorhamizah.binti@ibg.edu.tr
Güner EKİZ DİNÇMAN
Visiting Researcher
None
Former Personnel
Rıdvan ÖRKÜT
R&D Personnel
ridvan.orkut@ibg.edu.tr
+90 232 299 41
00
(4001)
Gizem YILMAZER ALTUN
R&D Personnel
gizem.yilmazer@ibg.edu.tr
Cemre YAŞAR
Research Technician
cemre.yasar@ibg.edu.tr
Rıdvan ÖRKÜT
R&D Personnel
ridvan.orkut@ibg.edu.tr
+90 232 299 41
00
(4001)
Olcay MERT
R&D Personnel
olcay.mert@ibg.edu.tr
Umut EKİN
Research Assistant
umut.ekin@ibg.edu.tr
Tuğçe BATUR
Research Assistant
tugce.batur@ibg.edu.tr
Seyhan İÇİER
R&D Personnel
seyhan.icier@ibg.edu.tr
Semiramis YILMAZ
Researcher
semiramis.yilmaz@ibg.edu.tr
Fatih MAMAK
Undergraduate Student
fatih.mamak@ibg.edu.tr
Erhan ÇITAK
MSc Student
erhan.citak@msfr.ibg.edu.tr
Hakan SOYTÜRK
MSc Student
hakan.soyturk@ibg.edu.tr
Mehmet Can UÇAR
Undergraduate Student
can.ucar@msfr.ibg.edu.tr
Şeyda GÜLLÜ
MSc Student
seyda.gullu@ibg.edu.tr
Vedat SARI
Undergraduate Student
vedat.sari@ibg.edu.tr
Ceren ÖZER ÇOKGEZME
Researcher
ceren.ozer@ibg.edu.tr
Hasan Onur ÇAĞLAR
Post-Doc Researcher
hasan.caglar@msfr.ibg.edu.tr
Gizem ARIK
Post-Doc Researcher
gizem.arik@msfr.ibg.edu.tr
Gizem BOSKAN
PhD Student
gizem.boskan@msfr.ibg.edu.tr
Bahriye KARAKAŞ KÖSE
Post-Doc Researcher
bahriye.karakas@ibg.edu.tr
Sıla KAHYAOĞLU
Visiting Researcher
sila.kahyaoglu@ibg.edu.tr
Bilgünay İlkin SAFA
Undergraduate Student
ilkin.safa@ibg.edu.tr
Ayça URAS
MSc Student
None
Büşra ERSAYAN
Undergraduate Student
busra.lulaci@ibg.edu.tr
Cevriye PAMUKÇU
Post-Doc Researcher
None
Bilgünay İlkin SAFA
Undergraduate Student
ilkin.safa@ibg.edu.tr
Tuğçe CANAVAR YILDIRIM
Researcher
tugce.yildirim@ibg.edu.tr
Ceren ÖZER ÇOKGEZME
PhD Student
ceren.ozer@ibg.edu.tr
Muzaffer YILDIRIM
Researcher
muzaffer.yildirim@ibg.edu.tr
Zeynep Sena KARAHAN
PhD Student
zeynepsena.karahan@ibg.edu.tr
Serra ÖZARI
PhD Student
serra.ozcan@ibg.edu.tr
Büşra ERSAYAN
Technician
busra.lulaci@ibg.edu.tr
Yağmur Tuçe AKYILDIZ
Researcher
None
Cengiz AKKALE
Researcher
cengiz.akkale@ibg.edu.tr
Buse ÇALOĞLU
Visiting Researcher
None
Kübra LAÇİN
Visiting Researcher
None
Ayça ÖZKAN
Researcher
ayca.ozkan@ibg.edu.tr
0 (232) 299 _ _
Nur Banu YILMAZ
MSc Student
banu.yilmaz@std.ibg.edu.tr
Selected Publications
Kalyoncu S, Sayili D, Kuyucu AZ, Soyturk H, Gullu S, Ersayan B, Tarman IO, Avci ME, Mert O, Haskok U, Tekin E, Akinturk H, Orkut R, Demirtas A, Tilmensagir I, Ulker C, Gungor B, Inan M. Development of a Recombinant Omicron BA.1 Subunit Vaccine Candidate in Pichia pastoris.. Microbial biotechnology. 2025 January ; 18 (1) : e70077. doi:10.1111/1751-7915.70077. Download
Kalyoncu S, Yilmaz S, Kuyucu AZ, Sayili D, Mert O, Soyturk H, Gullu S, Akinturk H, Citak E, Arslan M, Taskinarda MG, Tarman IO, Altun GY, Ozer C, Orkut R, Demirtas A, Tilmensagir I, Keles U, Ulker C, Aralan G, Mercan Y, Ozkan M, Caglar HO, Arik G, Ucar MC, Yildirim M, Yildirim TC, Karadag D, Bal E, Erdogan A, Senturk S, Uzar S, Enul H, Adiay C, Sarac F, Ekiz AT, Abaci I, Aksoy O, Polat HU, Tekin S, Dimitrov S, Ozkul A, Wingender G, Gursel I, Ozturk M, Inan M. Process development for an effective COVID-19 vaccine candidate harboring recombinant SARS-CoV-2 delta plus receptor binding domain produced by Pichia pastoris.. Scientific reports. 2023 March ; 13 (1) : 5224. doi:10.1038/s41598-023-32021-9. Download
Erden-Karaoğlan F, Karaoğlan M, Yılmaz G, Yılmaz S, İnan M. Deletion analysis of Pichia pastoris alcohol dehydrogenase 2 (ADH2) promoter and development of synthetic promoters.. Biotechnology journal. 2022 February ; 17 (2) : e2100332. doi:10.1002/biot.202100332. Download
Karaoğlan M, Erden-Karaoğlan F, Yılmaz S, İnan M. Identification of major ADH genes in ethanol metabolism of Pichia pastoris.. Yeast. 2020 February ; 37 (2) : 227-236. doi:10.1002/yea.3443. Download
Erden-Karaoğlan F, Karakaş-Budak B, Karaoğlan M, Inan M. Cloning and expression of pullulanase from Bacillus subtilis BK07 and PY22 in Pichia pastoris.. Protein expression and purification. 2019 October ; 162 : 83-88. doi:10.1016/j.pep.2019.05.008. Download
Türkanoğlu Özçelik A, Ersöz F, İnan M. Extracellular production of the recombinant bacterial transglutaminase in Pichia pastoris.. Protein expression and purification. 2019 July ; 159 : 83-90. doi:10.1016/j.pep.2019.03.003. Download
Ersöz F, İnan M. Large-scale production of yak (Bos grunniens) chymosin A in Pichia pastoris.. Protein expression and purification. 2019 February ; 154 : 126-133. doi:10.1016/j.pep.2018.10.007. Download
Türkanoǧlu Özçelik A, Yılmaz S, Gökbora S, İnan M. A quantitative polymerase chain reaction assay for the detection of equine (horse and donkey)-originated meat in processed bovine meat products.. Food science and technology international = Ciencia y tecnologia de los alimentos internacional. 2019 January ; 25 (1) : 38-46. doi:10.1177/1082013218794849. Download
Karaoglan M, Erden Karaoglan F. and Inan M.. Functional analysis of alcohol dehydrogenase (ADH) genes in Pichia pastoris. Biotechnol Lett. 2016 March ; 38 (3) : 463-9. doi:10.1007/s10529-015-1993-z. Download
Karaoglan M, Karaoglan FE, Inan M. Comparison of ADH3 promoter with commonly used promoters for recombinant protein production in Pichia pastoris. Protein Expr Purif. 2016 May ; 121 : 112-7. doi:10.1016/j.pep.2016.01.017. Download
Khasa YP, Conrad S, Sengul M, Plautz S, Meagher MM, Inan M. Isolation of Pichia pastoris PIR genes and their utilization for cell surface display and recombinant protein secretion. Yeast. 2011 March ; 28 (3) : 213-26. doi:10.1002/yea.1832. Download
Jacobs PP, Inan M, Festjens N, Haustraete J, Van Hecke A, Contreras R, Meagher MM, Callewaert N. Fed-batch fermentation of GM-CSF-producing glycoengineered Pichia pastoris under controlled specific growth rate. Microb Cell Fact. 2010 November ; 9 : 93. doi:10.1186/1475-2859-9-93. Download
Kane J, Inan M and Saraf R.F. Self-Assembled Nanoparticle Necklaces Network Showing Single-Electron Switching at Room Temperature and Biogating Current by Living Microorganisms. ACS Nano. 2010 ; 4 (1) : 317–323. doi:10.1021/nn901161w. Download
Total : 13
Selected Book Chapters
Pichia pastoris Promoters (2019). Recombinant Protein Production in Yeast. Humana Press, New York, NY.
Total : 1
Projects
The Scientific and Technological Research Council of Turkey - TUBITAK - RD : Target Specific Pan-Cancer Therapies (PAN-TER), Ongoing
The Scientific and Technological Research Council of Turkey - TUBITAK - RD : Development of Pichia pastoris Expression Strains for Large Scale Biopharmaceutical Production via Metabolic Engineering Tools, Ongoing
European Union - Infrastructure : RareBoost - Boosting the Rare Disease research and innovation capacity of the Izmir Biomedicine and Genome Center, Ongoing
The Scientific and Technological Research Council of Turkey - TUBITAK - RD : Development of Recombinant Protein Based Vaccine Against SARS-CoV-2, Ongoing
The Scientific and Technological Research Council of Turkey - TUBITAK - RD : Development of Drugs Based on “Ghost Receptor-Antibody” Against SARS-CoV-2, Ongoing
Patents
- Danielle Marie Mitchell, Leon F. Garcia-Martinez, Patricia Dianne McNeill, Ethan Wayne Ojala, Mehmet Inan,John Latham 2022 , Multi-copy strategy for high-titer and high-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris, US11225667B2
- Mitchell, D.M., Garcia-Martinez, L.F., McNeill, P.D., Ojala, E.W., Inan, M. and Latham, J. 2018 , Multi-copystrategy for high-titer and high-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris, US10150968B2
- Mehmet İNAN 2010 , PiPichia pastoris PIR1 secretion signal peptide for recombinant protein expression and Pichia pastoris PIR1 and PIR2 anchor domain peptides for recombinant surface display, US7741075B2
- Mehmet Inan, Michael M. Meagher Andrew K. Benson 2004 , Alcohol oxidase 1 regulatory nucleotide sequences for heterologous gene expression in yeast, US6699691B2
Contact
IBG-PHARMA Platform
Platform Director
Mehmet İNAN
mehmet.inan@ibg.edu.tr
+90 232 299 41 00
(1004 - 5271)
+9
02322994114