Platform Director

Mehmet İNAN
+90 232 299 41 00 (5271)
+9 0 (232) 299 41 77

Rıdvan ÖRKÜT R&D Personnel
+90 232 299 41 00 (4001)

Gizem YILMAZER ALTUN R&D Personnel

Hasan Onur ÇAĞLAR Post-Doc Researcher

Doğu SAYILI Molecular Cell Biologist

Gizem ARIK Post-Doc Researcher

Olcay MERT Research Technician

Ayça ZEYBEK KUYUCU Researcher

Ceren ÖZER Research Technician

Hüseyin AKINTÜRK Research Technician

Cemre YAŞAR Research Technician

Semiramis YILMAZ Researcher

Hakan SOYTÜRK Undergraduate Student

Erhan ÇITAK MSc Student

Selected Publications

Erden-Karaoğlan F, Karakaş-Budak B, Karaoğlan M, Inan M. Cloning and expression of pullulanase from Bacillus subtilis BK07 and PY22 in Pichia pastoris.. Protein expression and purification. 2019 October ; 162 : 83-88. doi:10.1016/j.pep.2019.05.008.

Türkanoğlu Özçelik A, Ersöz F, İnan M. Extracellular production of the recombinant bacterial transglutaminase in Pichia pastoris.. Protein expression and purification. 2019 July ; 159 : 83-90. doi:10.1016/j.pep.2019.03.003.

Ersöz F, İnan M. Large-scale production of yak (Bos grunniens) chymosin A in Pichia pastoris.. Protein expression and purification. 2019 February ; 154 : 126-133. doi:10.1016/j.pep.2018.10.007.

Türkanoǧlu Özçelik A, Yılmaz S, Gökbora S, İnan M. A quantitative polymerase chain reaction assay for the detection of equine (horse and donkey)-originated meat in processed bovine meat products.. Food science and technology international = Ciencia y tecnologia de los alimentos internacional. 2019 January ; 25 (1) : 38-46. doi:10.1177/1082013218794849.

Karaoğlan M, Erden-Karaoğlan F, Yılmaz S, İnan M. Identification of major ADH genes in ethanol metabolism of Pichia pastoris.. Yeast (Chichester, England). 2019 October . doi:10.1002/yea.3443.

Karaoglan M, Erden Karaoglan F. and Inan M.. Functional analysis of alcohol dehydrogenase (ADH) genes in Pichia pastoris. Biotechnol Lett. 2016 March ; 38 (3) : 463-9. doi:10.1007/s10529-015-1993-z.

Karaoglan M, Karaoglan FE, Inan M. Comparison of ADH3 promoter with commonly used promoters for recombinant protein production in Pichia pastoris. Protein Expr Purif. 2016 May ; 121 : 112-7. doi:10.1016/j.pep.2016.01.017.

Khasa YP, Conrad S, Sengul M, Plautz S, Meagher MM, Inan M. Isolation of Pichia pastoris PIR genes and their utilization for cell surface display and recombinant protein secretion. Yeast. 2011 March ; 28 (3) : 213-26. doi:10.1002/yea.1832.

Jacobs PP, Inan M, Festjens N, Haustraete J, Van Hecke A, Contreras R, Meagher MM, Callewaert N. Fed-batch fermentation of GM-CSF-producing glycoengineered Pichia pastoris under controlled specific growth rate. Microb Cell Fact. 2010 November ; 9 : 93. doi:10.1186/1475-2859-9-93.

Kane J, Inan M and Saraf R.F. Self-Assembled Nanoparticle Necklaces Network Showing Single-Electron Switching at Room Temperature and Biogating Current by Living Microorganisms. ACS Nano. 2010 ; 4 (1) : 317–323. doi:10.1021/nn901161w.

Total : 10

Selected Book Chapters

Pichia pastoris Promoters (2019). Recombinant Protein Production in Yeast. Humana Press, New York, NY.

Total : 1


  • Mehmet Inan, Michael M. Meagher Andrew K. Benson 2004 , Alcohol oxidase 1 regulatory nucleotide sequences for heterologous gene expression in yeast, US6699691B2
  • Mitchell, D.M., Garcia-Martinez, L.F., McNeill, P.D., Ojala, E.W., Inan, M. and Latham, J. , Multi-copystrategy for high-titer and high-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris, US10150968B2
  • Mehmet İNAN , PiPichia pastoris PIR1 secretion signal peptide for recombinant protein expression and Pichia pastoris PIR1 and PIR2 anchor domain peptides for recombinant surface display, US7741075B2



Platform Director

Mehmet İNAN
+90 232 299 41 00 (5271)
+9 0 (232) 299 41 77